06/18/2026
Low Dose Naltrexone has been around for decades, but it's having a moment in longevity medicine, and for good reason.
At low doses, LDN works by calming overactive immune cells that drive chronic inflammation. Chronic inflammation is so consistently linked to aging that researchers gave it its own name: inflamm-aging. It's the underlying driver of heart disease, Alzheimer's, diabetes, fatigue, and brain fog — conditions that often share the same root cause even when they're treated separately.
LDN is a core component of our XPRIZE Healthspan clinical trial, alongside Rapamycin, NAD+, exercise, and other targeted interventions. Our goal is to reverse markers of muscle, immune, and brain aging by 10 to 20 years. In our initial study, participants in the treatment group saw improvements in immune function, energy levels, and slower biological aging.
Inflammation doesn't have to be an accepted part of getting older.
Learn more about LDN at the link in bio.
(For educational purposes only)