10/25/2025
Bahji, Anees, et al. “Pharmacotherapies for Cannabis Use Disorder: A Systematic Review and Network Meta-Analysis.” International Journal of Drug Policy, vol. 97, no. 49(2), Nov. 2021, p. 103295, https://doi.org/10.1016/j.drugpo.2021.103295.
This article reviews different medications that researchers have tested to help people with cannabis addiction. It goes over several drugs, like nabilone and gabapentin, that might ease withdrawal or reduce cravings. Even though none of the medication completely solve the problem, the study shows that science is getting closer to finding helpful options. I decided to use this article because it connects the medical and psychological sides of treatment. It helped me understand that medication can support recovery, but that counseling and behavioral therapy are still very important parts of the process.
Petrilli, Kat, et al. “Association of Cannabis Potency with Mental Ill Health and Addiction: A Systematic Review.” The Lancet Psychiatry, vol. 9, no. 9, Sept. 2022, pp. 736–750, https://doi.org/10.1016/s2215-0366(22)00161-4.
This study looked at how the strength of cannabis affects mental health and the chances of becoming addicted, The authors found that the higher the THC level, the more likely people were to develop problems like anxiety, psychosis, or dependence. They also noticed that people using stronger cannabis tended to start using daily and had more withdrawal symptoms when they tried to stop. I chose this article because it shows how much cannabis has changed over time. It’s not the same mild drug people remember from decades ago. This helps me see that potency really matter when studying addiction and that stronger forms can have a serious impact on both the mind and behavior.
Gowin, Joshua L, et al. “Brain Function Outcomes of Recent and Lifetime Cannabis Use.” JAMA Network Open, vol. 8, no. 1, 2 Jan. 2025, jamanetwork.com/journals/jamanetworkopen/fullarticle/2829657, https://doi.org/10.1001/jamanetworkopen.2024.57069.
This article focuses on how cannabis use changes brain function over time. The researchers used brain scans to compare people who had used cannabis heavily for years with those who hadn’t. They found that heavy users had less activity in parts of the brain that control focus, memory, and decision-making. Even when they weren’t high. I included this article because it helps me understand the brain on a biological level. It’s one thing to say that ma*****na affects motivation and attention, but seeing research that visually shows the changes in brain scans really helps it makes sense.
Batalla, A, et al. “The Neuropsychopharmacology of Cannabis: A Review of Human Imaging Studies.” Pharmacology & Therapeutics, vol. 195, no. 92, 1 Mar. 2019, pp. 132–161, www.sciencedirect.com/science/article/pii/S0163725818301906, https://doi.org/10.1016/j.pharmthera.2018.10.006.
This article reviews brain imaging studies to explain how cannabis affects different parts of the brain. It shows that THC changes the activity in areas responsible for emotions, memory, and reward. It also talks about how CBD seems to have the opposite effect and might balance out some of THC’s negative impacts, even though this source is a few years older, it’s helpful for understanding the science behind how ma*****na interacts with the brain. I included is because it gives a strong foundation for my project and helps me see how cannabis can cause short- and long-term changes that play a role in addiction.
Ghafouri, Mohammad, et al. “Treatments for Cannabis Use Disorder across the Lifespan: A Systematic Review.” Brain Sciences, vol. 14, no. 3, 1 Mar. 2024, p. 227, www.mdpi.com/2076-3425/14/3/227, https://doi.org/10.3390/brainsci14030227.
This review looks a different type of treatment for cannabis addiction and how they work for people of different ages. It explains that therapy approaches like cognitive0behavioral therapy (CBT) and motivational enhancement therapy (MET) are most effective overall, especially when used with support groups or family involvement. Medications show mixed results depending on the persons age and how much they use. I chose this article because it reminds me that addiction treatment isn’t one-size-fits-all. It helped me see that younger and older users might need different kinds of support when it comes to recovery.